Paget's disease of bone - How is it diagnosed and treated?

Unexplained bone pain or deformities shouldn't be ignored. Understanding Paget's disease of bone is the first critical step toward getting a proper diagnosis, preventing serious complications like fractures, and starting effective treatment.

What are the main causes of Paget's Disease of Bone?

• The exact causes of Paget's disease are still unknown, but researchers believe a combination of genetic and environmental factors are likely involved.
• A family history of the condition significantly increases your risk, suggesting that certain inherited genes can make you more susceptible to the disease.
• Some theories suggest that a slow-acting viral infection, contracted years earlier, may trigger the abnormal bone remodeling process in genetically susceptible individuals.

Key symptoms of Paget's Disease of Bone to watch for

• The most common of Paget's disease symptoms is persistent bone pain, which can occur in any bone but is often felt in the spine or pelvis.
• Abnormal bone remodeling can lead to enlarged or misshapen bones, bowed legs, an enlarged skull, and an increased risk of painful bone fractures.
• While not a visible symptom, blood tests often reveal elevated levels of alkaline phosphatase, a key indicator of rapid bone turnover in the body.

How can you prevent Paget's Disease of Bone effectively?

• Since the exact causes of Paget's disease are not fully understood, there is currently no known way to prevent it from developing.
• The key to preventing serious complications is early diagnosis, often prompted by abnormal x-rays or blood tests performed for other medical reasons.
• Once diagnosed, preventing fractures involves regular monitoring, a diet rich in calcium and vitamin D, and appropriate physical activity to maintain bone strength.

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While there is no cure, effective Paget's disease treatment can manage symptoms and slow progression. If you have concerns, consult a specialist to discuss treatment with bisphosphonates and protect your bone health.

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